Murray reflects on painful loss to Titans: "This might be No. 1."

The Arizona Cardinals suffered a heartbreaking 22-21 loss to the Tennessee Titans, marking their third consecutive defeat decided by a walk-off field goal—a first in NFL history since the merger.

Why it matters: This latest loss not only highlights the Cardinals' struggles but also raises questions about their ability to close out games while putting pressure on head coach Jonathan Gannon and quarterback Kyler Murray.

• The Cardinals held a commanding 21-3 lead before surrendering 19 unanswered points in the second half.
• This game exemplifies the fine line between victory and defeat in the modern NFL, where momentum can quickly shift.

What’s new: The Cardinals were unable to score after an impressive first quarter, managing just 14 points despite accumulating 224 total yards afterward.

• Marvin Harrison Jr. showcased his talent with three catches for 79 yards in the opening minutes.
• Conversely, the team was plagued by critical errors that ultimately cost them the game.

By the numbers: Emari Demercado's costly fumble marked the longest rushing play ending in a lost fumble since 1978, underscoring the significance of execution at crucial moments.

• Arizona committed eight penalties, including two pre-snap infractions and a holding penalty that negated a 32-yard pass, contributing to their offensive woes.
• Teams that hold a 22-point lead entering the fourth quarter have historically won 1,276 times and lost only once over the past 25 seasons.

Yes, but: Despite the mistakes, Murray expressed confidence in his teammates, particularly in Demercado, emphasizing that such lapses are uncharacteristic for players of their caliber.

• "I know his character. I know his IQ of the game," said Murray, highlighting his belief in the team's potential to overcome adversity.

What to watch: Moving forward, the Cardinals must address these mistakes as they prepare for upcoming games, focusing on discipline and execution under pressure.

• With Murray's leadership, the team will need to rebound quickly and learn from this painful experience to avoid further losses.

The bottom line: The Cardinals inability to maintain their lead against the Titans raises concerns about their mental fortitude and closing ability, crucial elements for any team aspiring to compete in the playoffs.